ScienceDirect - Neuromuscular Disorders : Pneumothorax associated with long-term non-invasive positive pressure ventilation in Duchenne muscular dystrophy*1


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Neuromuscular Disorders
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doi:10.1016/j.nmd.2004.03.002

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Copyright © 2004 Published by Elsevier Science B.V.

Case report

Pneumothorax associated with long-term non-invasive positive pressure ventilation in Duchenne muscular dystrophy ^*1

Andrea Vianello ^,, Giovanna Arcaro^a, Federico Gallan^a, Carlo Ori^b and Matteo Bevilacqua^a

^a Unità di Terapia Semi-Intensiva Respiratoria, Azienda Ospedaliera di Padova, Padova, Italy
^b Sezione di Anestesia e Rianimazione, Dipartimento di Farmacologia, Università di Padova, Padova, Italy

Received 11 December 2003; Revised 1 March 2004; accepted 4 March 2004. Available online 27 April 2004.

Abstract

Long-term non-invasive positive pressure ventilation (NPPV) is effective for improving the quality of life and survival of neuromuscular patients. This treatment is usually easy to administer and severe complications have rarely been reported. We describe two cases in which the development of pneumothorax was associated with long-term NPPV administered to Duchenne muscular dystrophy patients. Given the wide scale utilization of chronic NPPV, we suggest that care-givers and patients be made aware of this serious complication.

Author Keywords: Duchenne muscular dystrophy; Pneumothorax; Non-invasive positive pressure ventilation

CRF, chronic respiratory failure; DMD, Duchenne muscular dystrophy; NPPV, non-invasive positive pressure ventilation; PTV, pressure targeted ventilation; VTV, volume targeted ventilation; IPAP, inspiratory positive airway pressure; EPAP, expiratory positive airway pressure

Corresponding author. Address: U.O. Fisiopatologia Respiratoria, Azienda Ospedaliera di Padova, Via Giustiniani, 2, 35128 Padova, Italy

*1 This work was performed at University Hospital, Padova, Italy.

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Neuromuscular Disorders
Article in Press, Corrected Proof

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